Journal of Clinical Case Reports Medical Images and Health Sciences

Hydroxyurea and Sperm Abnormalities in Patients with Sickle Cell Disease by Dr. Salma M. AlDallal in Journal of Clinical Case Reports Medical Images and Health Sciences   ABSTRACT Hydroxyurea is a key treatment option for patients having sickle cell disease. Although the treatment has been effective in improving the survival rate, new concerns over improving quality of life are forthcoming due to spermatogenesis-related toxicities and teratogenic effects. The available evidence shows that hydroxyurea might exacerbate the existing sperm abnormalities. There is a lack of comprehensive, systemic evidence to demonstrate the precise effects and role of hydroxyurea on sperm abnormalities in patients with sickle cell disease. Patients and healthcare providers require accurate and extensive information on sperm-related toxicities to make informed decisions. Here, I discuss the effects of hydroxyurea (HU) on sperm parameters, clinical study evidence, and treatment options available for fer...

Prevention and rehabilitation in Middle Ages by Prof. Francesco Carelli in Journal of Clinical Case Reports Medical Images and Health Sciences Italian hospitals in the late Middle Ages already offered much more than a simple reception and care.  In a work that can be consulted in the Laurentian Library in Florence, datable about 1300,  painter Gaddi shows a series of hospitalized people. Already the representation is not very sad perhaps due to the lack of modern white walls and patients appear regularly placed in beds with acts of assistance and care.  The two couples in the foreground completely decline an idea of health that we moderns tend to, even though we have not yet reached it.  In fact, therapy is combined with education and prevention.   The disease in question is a chronic vascular sore, a subject not resolved at by us moderns and a source of great health care costs.    One of the reasons for these costs is to be fund in the lac...

A contemporary clinical reasoning and multi-dimensional approach of Lower back pain management by Dr. Sarma S.T in Journal of Clinical Case Reports Medical Images and Health Sciences ABSTRACT The incidence rate of low back pain (LBP) is expanding in every clinical context as it is a common musculoskeletal illness affecting the overall population although the frequency of back pain and functional impairment increasing with age. This leads to tremendous strain as it represents one of the leading causes for growing disability and major socioeconomic burden in almost every healthcare system globally thus an efficient back pain management strategy is an urgent priority. This review is to outline the common causes, associated risk factors, clinical presentation and contemporary clinical reasoning including multi-dimensions of pain aspects to assess the patients with low back pain for achieving the precise clinical decision making as it would be a provision to implement potential tactics to...

Obsessive Compulsive Disorder in Palestine: A Literature Review by Israa M. Sawalha in Journal of Clinical Case Reports Medical Images and Health Sciences Abstract Methods A computerized literature searches (Google Scholar, PubMed, Science Direct, Springer Link, Elsevier, Semantic Scholar, and HINARI) was used to collect studies addressing the OCD in Palestine. Results and Conclusion OCD in Palestine is widely presented in adolescence and children at a young age. The most common type of OCD in Palestine is checking type. Set of risk factors increases developing OCD, including sexual abuse at any age as well as anxiety, depression, phobia and somatization disorders. In addition, the family incomes play a big role in presenting OCD, especially low income families. Most of the patients who have OCD were depressed and complaining of stigma and ignorance. Recommendations include getting rid of the stigma, creating a chance for low income families, further studies into OCD in Palestine, en...